6180 Henderson Road

Long admired as one of Sanibel Island’s most distinctive and enchanting residences, this extraordinary estate blends the timeless elegance of Franciscan mission-style architecture with exquisite hand-carved Mexican sandstone details.Nestled among meticulously curated grounds, the home is a botanical haven, showcasing rare and exotic specimen vegetation collected from around the globe. Beyond antique barn doors, the entry reveals a grand, light-filled great room that draws your gaze toward a stunning freeform pool and an expansive, fenced-in backyard. Perfectly positioned on the water’s edge, the outdoor space also features a chic, custom-designed shed—ideal as a studio, garden retreat, or stylish entertaining nook. Inside, the open-concept design seamlessly integrates luxury and function. The gourmet kitchen is a culinary showpiece, showcasing Crystal countertops, Café appliances, and bespoke cabinetry. Adjacent to the kitchen, a spacious butler’s pantry and a multifunctional laundry/office room offer thoughtful convenience. The primary suite serves as a serene private retreat, complete with tranquil views and direct walk-out access to the heated pool. For boating enthusiasts, this property offers direct access to the water and an oversized dock equipped with a 10,000-pound lift—mere minutes to the open waters of San Carlos Bay. Located in one of Sanibel Island’s most coveted enclaves near The Sanctuary, this residence offers a lifestyle of privacy, elegance, and exceptional boating—all wrapped in architectural artistry rarely found on the island. Community boat ramp at the end of Henderson. Owner is a licensed Florida Real Estate Broker